My experience was the fish will go off food while on the metro, The idea behind raising the temp. is one to weaken the parasite and two, the medicine is a human medicine and our body temp is at least 96. You can decide on the temp thing , discus can take it but you need to research if the the other organisms in your tank can. Epsom salts are good to do before you start the metro, it will flush out the intestines. Just my experience (had a bad one with live blackworms). I also would dose in the morning and 10 hours later, then a water change in the morning, keep the lights off also. I agree if the metro is going to work 5-7 days is plenty if it is going to work. Not a doctor, just a guy with a bad live blackworm problem and 500 gallons of water to be treated.