The medication " Clout " has been mentioned several times recently on the forum. A few decades ago that medication was pretty popular in fish circles. It was a very useful shotgun medication fir external things. It was removed from market because it contains trichlorfon a type of pesticide . It was definitely not a safe medication to use but it was useful if carefully used.
I was curious what was actually in it and did some digging.
I came across a Dr. Erik Johnson article on this very subject.
According to Dr.Johnson...
Im a biologist by background, I really dont get chemistry very well so I can't confirm that this article is accurate but I believe it to be ...and it makes sense from having used all tbose ingredients before.
The article then goes on to alternatives and discusses how for flukes.. praziquantel is more effective than trichlorfon . I believe that to be the case as well. I think the only real benefit of the trichlorfon was that it worked differently than praziquantel. Thats helpful when flukes are resistent to prazi. The article is pretty interesting especially if you are not really familar with fish medications.
I guess the take home is if you used "Clout" in the past and miss it, you should be able to get similar effects using metronidazole,praziquantel, and malachite green. I eould not combine these agents though as we dont really know the concentration of each or if they had to be modified to work together. There are products that combine metronidazole and Praziquantel though.
Just sharing .. not advocating the use of any of these alone or combined.
Al
I was curious what was actually in it and did some digging.
I came across a Dr. Erik Johnson article on this very subject.
According to Dr.Johnson...
This is what was in Mardel’s Clout.
4-[p-(dimethylamino)-)O-phenylbenzylidene]-2, 5-cyclohexadien-1-xylidene dimethylammonium chloride –> That’s Malachite Green
dimethyl (2,2,2-trichloro-1-hydroxyethel) phosphonate; —> That’s trichlorfon
1,2-dimethyl-5-nitroimidazole –> That’s metronidazole
4-[p-(dimethylamino)-)O-phenylbenzylidene]-2, 5-cyclohexadien-1-xylidene dimethylammonium chloride –> That’s Malachite Green
dimethyl (2,2,2-trichloro-1-hydroxyethel) phosphonate; —> That’s trichlorfon
1,2-dimethyl-5-nitroimidazole –> That’s metronidazole
The article then goes on to alternatives and discusses how for flukes.. praziquantel is more effective than trichlorfon . I believe that to be the case as well. I think the only real benefit of the trichlorfon was that it worked differently than praziquantel. Thats helpful when flukes are resistent to prazi. The article is pretty interesting especially if you are not really familar with fish medications.
I guess the take home is if you used "Clout" in the past and miss it, you should be able to get similar effects using metronidazole,praziquantel, and malachite green. I eould not combine these agents though as we dont really know the concentration of each or if they had to be modified to work together. There are products that combine metronidazole and Praziquantel though.
Just sharing .. not advocating the use of any of these alone or combined.
Al
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